Recent results from BRAHMS

The BRAHMS collaboration ended its data collection program in 2006. We are now well advanced in the analysis of a comprehensive set of data that spans systems ranging in mass from p+p to Au+Au and in energy from $\sqrt{s_{NN}} = 62.4$ to 200 GeV. Our analysis has taken two distinct paths: we explore the rapidity dependence of intermediate and high-transverse-momentum, identified-particle production, thus helping to characterize the strongly-interacting quark-gluon plasma (sQGP) formed at RHIC; we also explore particle yields at lower transverse momentum to develop a systematic understanding of bulk particle production at RHIC energies.Comment: 8 pages, 5 figures, presented at the 20th International Conference on Ultra-Relativistic Nucleus-Nucleus Collisions, "Quark Matter 2008", Jaipur, India, February 4-10, 200

Default mode network connectivity and reciprocal social behavior in 22q11.2 deletion syndrome

22q11.2 deletion syndrome (22q11DS) is a genetic mutation associated with disorders of cortical connectivity and social dysfunction. However, little is known about the functional connectivity (FC) of the resting brain in 22q11DS and its relationship with social behavior. A seed-based analysis of resting-state functional magnetic resonance imaging data was used to investigate FC associated with the posterior cingulate cortex (PCC), in (26) youth with 22qDS and (51) demographically matched controls. Subsequently, the relationship between PCC connectivity and Social Responsiveness Scale (SRS) scores was examined in 22q11DS participants. Relative to 22q11DS participants, controls showed significantly stronger FC between the PCC and other default mode network (DMN) nodes, including the precuneus, precentral gyrus and left frontal pole. 22q11DS patients did not show age-associated FC changes observed in typically developing controls. Increased connectivity between PCC, medial prefrontal regions and the anterior cingulate cortex, was associated with lower SRS scores (i.e. improved social competence) in 22q11DS. DMN integrity may play a key role in social information processing. We observed disrupted DMN connectivity in 22q11DS, paralleling reports from idiopathic autism and schizophrenia. Increased strength of long-range DMN connectivity was associated with improved social functioning in 22q11DS. These findings support a \u27developmental-disconnection\u27 hypothesis of symptom development in this disorder

On the Equation of State of Nuclear Matter in 158A GeV Pb+Pb Collisions

Within a hydrodynamical approach we investigate the sensitivity of single inclusive momentum spectra of hadrons in 158A GeV Pb+Pb collisions to three different equations of state of nuclear matter. Two of the equations of state are based on lattice QCD results and include a phase transition to a quark-gluon plasma. The third equation of state has been extracted from the microscopic transport code RQMD under the assumption of complete local thermalization. All three equations of state provide reasonable fits to data taken by the NA44 and NA49 Collaborations. The initial conditions before the evolution of the fireballs and the space-time evolution pictures differ dramatically for the three equations of state when the same freeze-out temperature is used in all calculations. However, the softest of the equations of state results in transverse mass spectra that are too steep in the central rapidity region. We conclude that the transverse particle momenta are determined by the effective softness of the equation of state during the fireball expansion.Comment: 4 pages, including 4 figures and 2 tables. For a PostScript file of the manuscript, you can also goto http://t2.lanl.gov/schlei/eprint.htm

Disrupted working memory circuitry and psychotic symptoms in 22q11.2 deletion syndrome

22q11.2 deletion syndrome (22q11DS) is a recurrent genetic mutation that is highly penetrant for psychosis. Behavioral research suggests that 22q11DS patients exhibit a characteristic neurocognitive phenotype that includes differential impairment in spatial working memory (WM). Notably, spatial WM has also been proposed as an endophenotype for idiopathic psychotic disorder, yet little is known about the neurobiological substrates of WM in 22q11DS. In order to investigate the neural systems engaged during spatial WM in 22q11DS patients, we collected functional magnetic resonance imaging (fMRI) data while 41 participants (16 22q11DS patients, 25 demographically matched controls) performed a spatial capacity WM task that included manipulations of delay length and load level. Relative to controls, 22q11DS patients showed reduced neural activation during task performance in the intraparietal sulcus (IPS) and superior frontal sulcus (SFS). In addition, the typical increases in neural activity within spatial WM-relevant regions with greater memory load were not observed in 22q11DS. We further investigated whether neural dysfunction during WM was associated with behavioral WM performance, assessed via the University of Maryland letter-number sequencing (LNS) task, and positive psychotic symptoms, assessed via the Structured Interview for Prodromal Syndromes (SIPS), in 22q11DS patients. WM load activity within IPS and SFS was positively correlated with LNS task performance; moreover, WM load activity within IPS was inversely correlated with the severity of unusual thought content and delusional ideas, indicating that decreased recruitment of working memory-associated neural circuitry is associated with more severe positive symptoms. These results suggest that 22q11DS patients show reduced neural recruitment of brain regions critical for spatial WM function, which may be related to characteristic behavioral manifestations of the disorder

Quasi-Elastic Scattering Studies of Water Diffusion

Quasi-elastic neutron scattering is a powerful method to study the dynamics of protons in biological systems. The technique has been used both for the study of water diffusion and protein motion. The neutron scattering measurements on water show that the translational and rotational diffusion coefficients in biological systems are reduced from bulk values. We review the measurements on water in frog muscle, cysts of artemia, and phycocyanin. Measurements on dry trypsin and trypsin-D2O solutions over the temperature range 75-300K show that there is proton motion at the one angstrom level even in the dry or frozen state

Nuclear Modification Factor for Charged Pions and Protons at Forward Rapidity in Central Au+Au Collisions at 200 GeV

We present spectra of charged pions and protons in 0-10% central Au+Au collisions at $\sqrt{s_{NN}}=200$ GeV at mid-rapidity ($y=0$) and forward pseudorapidity ($\eta=2.2$) measured with the BRAHMS experiment at RHIC. The spectra are compared to spectra from p+p collisions at the same energy scaled by the number of binary collisions. The resulting nuclear modification factors for central Au+Au collisions at both $y=0$ and $\eta=2.2$ exhibit suppression for charged pions but not for (anti-)protons at intermediate $p_T$. The $\bar{p}/\pi^-$ ratios have been measured up to $p_T\sim 3$ GeV/$c$ at the two rapidities and the results indicate that a significant fraction of the charged hadrons produced at intermediate $p_T$ range are (anti-)protons at both mid-rapidity and $\eta = 2.2$

What's Interesting About Strangeness Production? - An Overview of Recent Results

In this paper I highlight a few selected topics on strange particle production in heavy-ion collisions. By studying the yield and spectra of strange particles we hope to gain understanding of the conditions reached in, and the ensuing dynamics of, the systems produced when ultra-relativistic heavy-ions are collided.Comment: 17 Pages, 18 figures, Hot Quarks 2004 Proceeding

Systematic Study of the Kaon to Pion Multiplicity Ratios in Heavy-Ion Collisions

We present a systematic study of the kaon to pion multiplicity ratios (K+/pi+ and K-/pi-) in heavy-ion collisions from AGS to RHIC energy using the Relativistic Quantum Molecular Dynamics (RQMD) model. The model satisfactorily describes the available experimental data on K+/pi+ and K-/pi-. Within the model, we find that the strong increase of the ratios with the number of participants is mainly due to hadronic rescattering of produced mesons with ingoing baryons and their resonances. The enhancement of K/pi in heavy-ion collisions with respect to elementary p+p interactions is larger at AGS energy than SPS energy, and decreases smoothly with bombarding energy. The total multiplicity ratios at RHIC energy are predicted by RQMD to be K+/pi+ = 0.19 and K-/pi- = 0.15.Comment: 10 pages, 8 figures, RevTeX style. A section is added to discuss effects of rope formatio

The New Physics at RHIC. From Transparency to High pt_t Suppression

Heavy ion collisions at RHIC energies (Au+Au collisions at $\sqrt{s_{NN}}=200$ GeV) exhibit significant new features as compared to earlier experiments at lower energies. The reaction is characterized by a high degree of transparency of the collisions partners leading to the formation of a baryon-poor central region. In this zone, particle production occurs mainly from the stretching of the color field. The initial energy density is well above the one considered necessary for the formation of the Quark Gluon Plasma, QGP. The production of charged particles of various masses is consistent with chemical and thermal equilibrium. Recently, a suppression of the high transverse momentum component of hadron spectra has been observed in central Au+Au collisions. This can be explained by the energy loss experienced by leading partons in a medium with a high density of unscreened color charges. In contrast, such high $p_t$ jets are not suppressed in d+Au collisions suggesting that the high $p_t$ suppression is not due to initial state effects in the ultrarelativistic colliding nuclei.Comment: 15 pages, 11 figures. to appear in Nucl. Physics A. Invited talk at 'Nucleus-Nucleus Collisions 2003' conference, Mosco